Abstract:Vine tea belongs to the Vitaceae, the Ampelopsis and the Ampelopsis grossedentata. Vine tea is rich in flavonoids, among which dihydromyricetin (DMY) is the most important component. Scientific research has found that vine tea and its main components have various biological effects such as anti-cancer, anti-oxidation, lipid-lowering, anti-inflammation, anti-bacteria and anti-fatigue. Current studies have found that vine tea and its mainly active components participate in different biological functions via targeting some important genes and regulating signal transduction pathways, but the molecular mechanism of its effects is still unclear. In this paper, the biological activities, signal transduction pathways and key target genes of vine tea and its main components were systematically reviewed according to the new progress at home and abroad in recent years. The paper will provide theoretical reference for the in-depth study of vine tea and its active components, and it also conducive to the further development and utilization of vine tea and its main active components in the future.