藤茶及二氢杨梅素的生物学功能研究进展
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中南林业科技大学

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湖南省研究生科研创新项目(CX2018B457) 中南林业科技大学研究生科技创新基金(20183010)。


The Progress of Biological Functions of Vine Tea and Dihydromyricetin
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中南林业科技大学

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    摘要:

    藤茶(vine tea)归属于葡萄科(Vitacea)蛇葡萄属(Ampelopsis Michx.)植物显齿蛇葡萄(Ampelopsis grossedentata)。藤茶中含有丰富黄酮类物质,其中最主成分为二氢杨梅素(dihydromyricetin, DMY)。科学研究发现藤茶及其主要活性成分具有抗癌、抗氧化、降脂、抗炎、抑菌和抗疲劳等生物学作用,目前的研究发现藤茶及其主要活性成分靶向一些重要基因和调控信号传导通路,参与不同的生物学功效,但其作用的分子机理尚不清楚。本文根据近年来国内外研究的新进展,对藤茶及其主要活性成分的生物活性、调控的信号传导通路和作用的关键靶基因等进行了系统综述,以期为藤茶及其活性成分的深入研究提供理论参考,也有利于今后进一步对藤茶及其主要活性成分的开发利用。

    Abstract:

    Vine tea belongs to the Vitaceae, the Ampelopsis and the Ampelopsis grossedentata. Vine tea is rich in flavonoids, among which dihydromyricetin (DMY) is the most important component. Scientific research has found that vine tea and its main components have various biological effects such as anti-cancer, anti-oxidation, lipid-lowering, anti-inflammation, anti-bacteria and anti-fatigue. Current studies have found that vine tea and its mainly active components participate in different biological functions via targeting some important genes and regulating signal transduction pathways, but the molecular mechanism of its effects is still unclear. In this paper, the biological activities, signal transduction pathways and key target genes of vine tea and its main components were systematically reviewed according to the new progress at home and abroad in recent years. The paper will provide theoretical reference for the in-depth study of vine tea and its active components, and it also conducive to the further development and utilization of vine tea and its main active components in the future.

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  • 收稿日期:2020-12-22
  • 最后修改日期:2021-01-06
  • 录用日期:2021-01-11
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