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文章摘要
阿洛酮糖酶法生产的研究进展
Recent advances on enzymatic production of D-allulose
投稿时间:2020-08-07  修订日期:2020-08-27
DOI:
中文关键词: D-阿洛酮糖  替代甜味剂  差向异构酶  生物转化
英文关键词: D-allulose, substitute sweetener, epimerase, biotransformation
基金项目:
作者单位E-mail
唐文娟 浙江华康药业股份有限公司 tangwenjuan@huakangpharma.com 
蔡雪 浙江工业大学  
程新平 浙江华康药业股份有限公司  
柳志强 浙江工业大学  
李勉 浙江华康药业股份有限公司 mian.li@huakangpharma.com 
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中文摘要:
      稀有单糖D-阿洛酮糖是D-果糖的C-3差向异构体,主要通过D-塔格糖3-差向异构酶或D-阿洛酮糖-3-差向异构酶对D-果糖进行异构化获得。D-阿洛酮糖不仅可以作为食品添加剂和膳食补充剂,而且具有改善胰岛素抵抗、增强抗氧化和降血糖控制等多种生理功能和健康益处。因此,D-阿洛酮糖作为传统高能量糖如蔗糖、果糖等的健康替代品,具有重要的开发与研究价值。本文综述了D-阿洛酮糖的理化性质、来源、体内代谢、生理功能、应用和最新生产技术,并讨论了D-阿洛酮糖生产中存在的问题及解决方案。针对低废物生成、低能耗、高糖产量等特点,也提出了一种绿色、可循环利用的D-阿洛酮糖生产工艺技术。
英文摘要:
      The rare monosaccharide D-allulose is the C-3 epimer of D-fructose, and is produced through the isomerization of D-fructose by D-tagatose 3-epimerases (DTEases) or D-allulose 3-epimerases (DAEases). D-Allulose can not only be used as a food ingredient and dietary supplement, but also exhibits a variety of physiological functions and health benefits such as improved insulin resistance, antioxidant enhancement, and hypoglycemic controls. Therefore, D-allulose has an important development value as a healthy alternative for conventional high-energy sugars such as sucrose and fructose. This review provided a systematic analysis of physicochemical property, existing sources, metabolism in vivo, functions, application, recent processing technologies of D-allulose. The existing problems and its proposed solutions for D-allulose production are discussed. A green and recyclable process technology for D-allulose production is also proposed for low waste formation, low energy consumption and high sugar yield.
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