食品中有害物苯并[a]芘诱导结肠毒性的研究进展
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Research Progress on Colonic Toxicity Induced by Foodborne Benzo[a]pyrene
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    摘要:

    苯并[a]芘是多环芳烃类物质,广泛存在于高温加工食品中,且工业生产和生活中燃料不完全燃烧也会产生大量苯并[a]芘,进而通过水源、空气和土壤等污染食物。流行病学调查显示,苯并[a]芘与结肠癌、结肠炎症等肠道疾病的发生密切相关。作者详细综述了不同食品中苯并[a]芘的含量,及其诱发结肠癌、结肠氧化损伤、结肠炎症、肠道菌群失调等结肠毒性的相关分子机制,以充分揭示食品有害物苯并[a]芘的结肠毒性,为其毒性控制和保障人体健康提供参考。

    Abstract:

    Benzo[a]pyrene is a kind of polycyclic aromatic hydrocarbon and widely found in high- temperature processed food. Moreover, incomplete combustion of fuel in industrial production and daily life also produce a huge number of benzo[a]pyrene, which further contaminates food through water, air and soil source. Epidemiological investigation shows that benzo[a]pyrene is closely related to colon cancer, colon inflammation and other intestinal diseases. Therefore, this paper summarized in detail the content of benzo[a]pyrene in different foods and the related molecular mechanisms of colonic toxicity that induce colon cancer, colon oxidative damage, colon inflammation and intestinal flora imbalance, aiming to fully reveal the colonic toxicity of foodborne benzo[a]pyrene and to provide a reference for its toxicity control and protection of human health.

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袁莉,王珠琳,李建科,张萌.食品中有害物苯并[a]芘诱导结肠毒性的研究进展[J].食品与生物技术学报,2021,40(8):9-16.

YUAN Li, WANG Zhulin, LI Jianke, ZHANG Meng. Research Progress on Colonic Toxicity Induced by Foodborne Benzo[a]pyrene[J]. Journal of Food Science and Biotechnology,2021,40(8):9-16.

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  • 在线发布日期: 2021-08-24
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