Abstract:Bile salt-stimulated lipase (BSSL) is a lipolytic enzyme. In the human body, BSSL is primarily secreted by the pancreas and is also found in the mammary glands during lactation, secreted with milk, which is one of the most abundant whey proteins. BSSL can hydrolyze a variety of substrates, including cholesteryl esters, fat-soluble vitamins, ceramide, etc., and plays a crucial role in the early digestion and absorption of milk lipids by newborns. Recent domestic and international studies have shown that in addition to promoting the digestion of milk fat in infants and young children, BSSL also plays significant roles in pathogen resistance, thrombosis regulation, inflammation modulation,atherosclerosis prevention and so on. The author summarizes the characteristics and functions of BSSL and explores its potential applications in infant formula.
