青刺尖“金花菌”发酵茶的降血脂效果
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S567.1;Q599;TS272.5

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Effect of Prinsepia utilis Fermented Tea on Hyperlipemia Mice
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    摘要:

    研究青刺尖茶经“金花菌”发酵后,其降血脂效果的变化。以普通饲料饲养小鼠作空白对照,饲喂高脂饲料建立高血脂症模型小鼠,再随机分成模型组、青刺尖“金花菌”发酵茶三个剂量处理组(2、6、9 g/kg)、青刺尖干茶组和血脂康组(3 g/kg)。各组分别连续灌胃处理28 d,心脏取血分离血清,检测总胆固醇(TC)、甘油三酯(TG)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)、载脂蛋白AI(Apo-AI)、载脂蛋白B(Apo-B)和脂蛋白a(LP-a);计算肝脏指数,并制作肝脏病理切片。与模型组比较,发酵茶三个剂量处理组的TC、TG、LDL-C及中剂量组的Apo-B/Apo-AI比值,均显著降低(p<0.05);发酵茶三个剂量组的HDL-C和肝脏指数,高剂量组的TC、中高剂量组的TG和LDL-C,差异均达到极显著(p<0.01),同时抑制了各处理组HDL-C的过度增加。与未发酵的青刺尖茶组比较,中、低剂量组小鼠的体重增长量较小,而低剂量组降低显著(p<0.05)。青刺尖茶经“金花菌”发酵后,能有效控制高血脂症小鼠体重的增加,更显著地降低或抑制高血脂症小鼠的各项生化指标,显现更优的降脂功效。

    Abstract:

    This paper studies the effect on hyperlipemia mice with the Prinsepia utilis tea which were be fermented by the "golden flower fungus". Hyperlipidemia mice were induced by intragastric administration of high fat forage,meanwhile,other mice were fed by standard normal diet as blank control group for 4 weeks. Then the heperlipidemia mice were randomly divided into 6 groups:the model group,the 3 doses of Prinsepia utilis fermented tea treatment groups(2,6,9 g/kg),the Prinsepia utilis dry tea group and the positive control group(3 g/kg). Respectively,each of the groups was treated by intragastric process for 28 days,then gained the serum by separating the heart blood,and detected the total cholesterol(TC),triglyceride(TG),high density lipoprotein cholesterol(HDL-C),low-density lipoprotein cholesterol(LDL-C),apolipoprotein AI(Apo-AI),apolipoprotein B(Apo-B) and lipoprotein a(LP-a). Calculate the liver index,then make the liver pathology section. Compared the 3 fermented tea treatment groups with the model group,TC,TG,LDL-C and the ratio of Apo-B to Apo-Ai was significantly lower(p<0.05). It has reached a very significant(p<0.01),the HDL-C and the liver index in the 3 doses fermented tea group,and TC,TG and LDL-C in the high dose group,meanwhile,curbing excessive increase of HDL-C in the treatment groups. Compared with the Prinsepia utilis dry tea group,it was not significant amount of weight gain in the medium and low dose fermented tea treatment groups,but significantly reduced in the low dose group(p<0.05). The Prinsepia utilis tea fermented by the "golden flower fungus",can effectively control the hyperlipidemia disease,decrease the weight gain of the mice,and significantly reduce or inhibit the biochemical indicators in hyperlipidemia mice,so with the help of golden flower fungus,biological indicator,especially,lipid-lowering can be appeared better efficacy than those without fermented tea.

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刘刚,杨妍,胡婷婷,邓钱江,张晓喻,黎霞.青刺尖“金花菌”发酵茶的降血脂效果[J].食品与生物技术学报,2018,37(3):323-328.

LIU Gang, YANG Yan, HU Tingting, DENG Qianjiang, ZHANG Xiaoyu, LI Xia. Effect of Prinsepia utilis Fermented Tea on Hyperlipemia Mice[J]. Journal of Food Science and Biotechnology,2018,37(3):323-328.

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  • 在线发布日期: 2018-06-08
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