Abstract:In this study we investigated the radioprotective activity of polysaccharide from purple sweet potato in mice irradiated by a 137Cs gamma(γ) ray(4.0 Gy,at a dose of 2.299×102C/kg·min-1).Mice were randomly divided into the control group and four experimental groups which were given polysaccharide from purple sweet potato(model group,low group,middle group,high group) for 30 days.The four experimental groups of mice were then exposed to 137Cs γ-rays and were given polysaccharide from purple sweet potato for a further 14 days.The number of white blood cells,the number of micronuclei in polychromatophilic erythrocytes of bone marrow in mice and the number of spleen colony-forming cells(CFU-S) were carefully determined.The activity of superoxide dismutase,glutathione peroxidase,catalase,malondialdehyde,spleen index and thymus index were also arrayed.The results indicated that the administration of polysaccharide from purple sweet potato is radioprotective in mice irradiated by 137Cs γ-rays in vivo.
