Research on the Purication of Polysialic Acid Based on the Property of the Fermentation Broth
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    Abstract:

    In order to obtain Polysialic acid(PSA) from the fermentation broth,the property of PSA and methods to remove the impurities in the fermentation broth were studied in this manuscript.The results demonstrated that PSA showed a good heat-stability and anti-alkalescence capability,and it was precipitated by ethanol and cetyl pyridinium chloride(CPC) in certain condition;impurities in the fermentation broth can be removed by filtration with Perlite as filter aid.Based on this,a novel PSA purification process was established.Through this process, the final PSA product was obtained with a purity and recovery(98.1±1.6)%and(56.1±1.7)%,respectively.

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LIU Jin-long, WU Jian-rong, SHENG Feng-dan, YU Dan-feng, ZHAN Xiao-bei. Research on the Purication of Polysialic Acid Based on the Property of the Fermentation Broth[J]. Journal of Food Science and Biotechnology,2010,29(6):931-936.

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  • Online: June 17,2014
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