Sober-Up Effect of Radix Puerariae and Flos Pueraria for Treating Acute Alcohol Poisoning Mice

doi:10.3969/j.issn.1673-1689.2012.06.010

Home > Archive>Volume 31, Issue 6, 2012 >621-627. DOI:10.3969/j.issn.1673-1689.2012.06.010

Sober-Up Effect of Radix Puerariae and Flos Pueraria for Treating Acute Alcohol Poisoning Mice
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                        10.3969/j.issn.1673-1689.2012.06.010
                    
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The target of this study is to compare the sober-up effect of Radix Puerariae and Flos Pueraria and the relationship of puerarin content and sober-up effect.For this,the sleeping time and the blood alcohol concentration of mice,that feed with the extract of Radix Puerariae or Flos Pueraria and feed and 5.75g/kg·bw alcohol after 30 min,were determined..It was found that t the sleeping time was decreaed by 43.3%(2.5 g/kg·bw) and 48.7%(7.5g/kg·bw) by PRW,and 51.1%(2.5 g/kg·bw).53.6%(7.5g/kg·bw) by PREThe mendium and high dose of PRW or PRE could inhibit absorption of alcohol and reduce the concentration of alcohol,and the high dose of PFWand PFE had a slightly effect on the alcohol concentration, only appearing Significant difference at 240 min.From the above results,it was concluded that the sober-up effect of Radix Puerariae is better than that of Flos Puerariaands a good positive correlation between the dose of puerarin in the PR and sober-up effect.

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GAO Xue-qing, WANG He-ya, QIAN He, XIA Rong-guang, ZHANG Fa-liang, ZHAO Xiao-lian. Sober-Up Effect of Radix Puerariae and Flos Pueraria for Treating Acute Alcohol Poisoning Mice[J]. Journal of Food Science and Biotechnology,2012,31(6):621-627.

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