Optimization of Fermentation Conditions for Cordycepin by Cordyceps militaris JN168
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    Abstract:

    The components for cordycepin production by Cordyceps militaris JN168 were optimized with single factor experiment and response surface methodology. The purpose of this study is to determine the best fermentation medium for cordycepin production by Cordyceps militaris JN168. Results showed that glucose and beef extract are the appropriate carbon and nitrogen sources with an optimal concentration of 40 g/L and 15 g/L,respectively. And adding inorganic salt is MgSO 4 , K 2 HPO 4 ,CaCl 2 and Na 2 HPO 4 with an optimal concentration of 0.76 g/L,0.63 g/L,0.66 g/L and 0.67 g/L respectively. The cordycepin concentration in the fermentation broth after optimization is 633.47 mg/L,which is 6 times before the optimization.

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YUE Cui-cui, SHEN Jian-zeng, CAI Yu-jie, LIAO Xiang-ru, LUO Jun-xia, ZHANG Da-bing. Optimization of Fermentation Conditions for Cordycepin by Cordyceps militaris JN168[J]. Journal of Food Science and Biotechnology,2013,32(2):135-141.

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  • Online: June 17,2014
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