Abstract:The sleep improvement effects of instant asparagus powder with different content of saponins on mice were studied in this paper.Methods:Healthy KM male mice with the body weight of 18～22g were divided into groups randomized and the direct sleep effect of the test material was observed.Then the mice were gavaged with instant asparagus powder A with 15% saponins,instant asparagus powder B with 50% saponins and positive control(Jujuboside) in different dosage every day,respectively.30 days later,the sleep-producing test with subthreshold dose of sodium pentobarbital,the incubation period test with barbital sodium and the sleep extending test with sodium pentobarbital were conducted.Results:both of the asparagus powder A and B have hypnotic sleep-producing effects under the threshold hypnotic dosage of pentobarbital sodium,and can significantly prolong sleep time induced by pentobarbital sodium;comparing with the control group,the difference of incubation periods with barbital sodium were significant for the asparagus powder A,not significant for the asparagus powder B,but the incubation periods have gradually shorten trend with the asparagus powder B in this experiment.Both of asparagus powder A and B have not function to improve sleep directly.Conclusion:Instant asparagus powder A and B can improve the sleeping quality of mice,and the asparagus powder A is more significant than asparagus powder B on sleep improvement effects in mice.
