Abstract:The hyperlipidemia model in SD rats was established and rats stomached in this manuscript. Through the determination of blood lipid and liver pathological changes in model rats, effect of Flat-European hybrid hazelnut oil on reducing blood lipid and preventing fatty liver were examined. The results showed that the levels of lipid between the model group and the control group were significantly different. The hyperlipidemia model was established. The rats gastric lavage results showed that rats fed soybean oil and Flat-European hybrid hazelnut oil low doses,middle doses and high doses total cholesterol(TC) content were significantly decreased by 13%,13%,16% and 16% compared to the high fat control group. Compared to the high fat control group rats triglyceride(TG) content were obviously different and reduced to 24%,24%,50% and 47%, respectively. Rats low density lipoprotein(LDL-C) content compared to the high fat control group were decreased by 1%,4%,6% and 26%. The rats high density lipoprotein(HDL-C) content were significantly increased 28%,32%,41% and 44%. Rats blood glucose(GLU),malonaldehyde(MDA),atherosclerosis index AI1,AI2 and coronary index(R-CHR) were significantly decreased and showed a positive correlation with hazelnut oil dose. Continuous feeding Flat-European hybrid hazelnut oil helped to reduce lipid deposition in liver in hyperlipidemia rats,had certain protective effect on rat liver cells.
