Study on Anti-Tumor Activities of WPOJ of Chemical Modification

doi:10.3969/j.issn.1673-1689.2014.04.006

Home > Archive>Volume 33, Issue 4, 2014 >368-373. DOI:10.3969/j.issn.1673-1689.2014.04.006

Study on Anti-Tumor Activities of WPOJ of Chemical Modification
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                        10.3969/j.issn.1673-1689.2014.04.006
                    
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The aim is to chemical modify WPOJ by using three kinds of methods, and to compare the anti-tumor activities of them before and after modification. The experiment made S-WPOJ with chlorosulfonic acid-pyridine method, the WPOJ was phosphorylated by phosphorylation regent and was carboxymethylated by isopropyl chloroucetate acid. The infrared spectrosocopy was adopted to test the structure of WPOJ before and after chemical modification, at the same time, its anti-tumor activities were also analysised by the MTT mothod before and after modification. and the result showed that there are characteristic absorption peak of sulfuric acid, phosphate groups, carboxymethyl groups after chemical modification WPOJ respectively, and the WPOJ of chemical modification have obviously improved anti-tumor activities at different levels and the anti-tumor activities of CWPOJ is the most strongest.

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ZHANG Xiaoping, SUN Runguang, WANG Xiaomei, ZHANG Lini. Study on Anti-Tumor Activities of WPOJ of Chemical Modification[J]. Journal of Food Science and Biotechnology,2014,33(4):368-373.

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Online: October 19,2014
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