Advances in Microbial Metabolic Engineering to Increase L-Threonine Production
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Q933

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    Abstract:

    As an essential amino acid for mammals,L-threonine has a wide application in the food,feeds,pharmaceutical and cosmetics industries. To date,L-threonine is almost exclusively produced through microbial fermentation. Metabolic engineering provides an effective means to strain development and thus to enhancing the L-threonine production. In this article,the pathway and regulation of L-threonine in the major industrial strains,Corynebacterium glutamicum and Escherichia coli are summarized,and advances on metabolic engineering to increase L-threonine production are reviewed.

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DONG Xunyan, WANG Xiaoyuan. Advances in Microbial Metabolic Engineering to Increase L-Threonine Production[J]. Journal of Food Science and Biotechnology,2016,35(12):1233-1240.

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  • Online: February 10,2017
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