Effect of Prinsepia utilis Fermented Tea on Hyperlipemia Mice

doi:10.3969/j.issn.1673-1689.2018.03.015

Home > Archive>Volume 37, Issue 3, 2018 >323-328. DOI:10.3969/j.issn.1673-1689.2018.03.015

Effect of Prinsepia utilis Fermented Tea on Hyperlipemia Mice
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                        10.3969/j.issn.1673-1689.2018.03.015
                    
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This paper studies the effect on hyperlipemia mice with the Prinsepia utilis tea which were be fermented by the "golden flower fungus". Hyperlipidemia mice were induced by intragastric administration of high fat forage，meanwhile，other mice were fed by standard normal diet as blank control group for 4 weeks. Then the heperlipidemia mice were randomly divided into 6 groups：the model group，the 3 doses of Prinsepia utilis fermented tea treatment groups（2，6，9 g/kg），the Prinsepia utilis dry tea group and the positive control group（3 g/kg）. Respectively，each of the groups was treated by intragastric process for 28 days，then gained the serum by separating the heart blood，and detected the total cholesterol（TC），triglyceride（TG），high density lipoprotein cholesterol（HDL-C），low-density lipoprotein cholesterol（LDL-C），apolipoprotein AI（Apo-AI），apolipoprotein B（Apo-B） and lipoprotein a（LP-a）. Calculate the liver index，then make the liver pathology section. Compared the 3 fermented tea treatment groups with the model group，TC，TG，LDL-C and the ratio of Apo-B to Apo-Ai was significantly lower（p<0.05）. It has reached a very significant（p<0.01），the HDL-C and the liver index in the 3 doses fermented tea group，and TC，TG and LDL-C in the high dose group，meanwhile，curbing excessive increase of HDL-C in the treatment groups. Compared with the Prinsepia utilis dry tea group，it was not significant amount of weight gain in the medium and low dose fermented tea treatment groups，but significantly reduced in the low dose group（p<0.05）. The Prinsepia utilis tea fermented by the "golden flower fungus"，can effectively control the hyperlipidemia disease，decrease the weight gain of the mice，and significantly reduce or inhibit the biochemical indicators in hyperlipidemia mice，so with the help of golden flower fungus，biological indicator，especially，lipid-lowering can be appeared better efficacy than those without fermented tea.

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LIU Gang, YANG Yan, HU Tingting, DENG Qianjiang, ZHANG Xiaoyu, LI Xia. Effect of Prinsepia utilis Fermented Tea on Hyperlipemia Mice[J]. Journal of Food Science and Biotechnology,2018,37(3):323-328.

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Online: June 08,2018
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