Study of Ganoderma lucidum Polysaccharides on Rat Anti-Fatigue and Anti-Oxidant Effect

doi:10.3969/j.issn.1673-1689.2018.05.015

Home > Archive>Volume 37, Issue 5, 2018 >555-559. DOI:10.3969/j.issn.1673-1689.2018.05.015

Study of Ganoderma lucidum Polysaccharides on Rat Anti-Fatigue and Anti-Oxidant Effect
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                        10.3969/j.issn.1673-1689.2018.05.015
                    
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To detect the normal rats，rats after exercise fatigue and exhaustion after 12 h of rest in rat liver tissue and mitochondria-related indicators of black Ganoderma lucidum polysaccharides enhance exercise capacity and fatigue and enhance the body's ability to recover after exercise influences. 100 male Wistar rats were randomly divided into five groups：control group（A），exhaustive group（B），exhaustive rest group（C），black Ganoderma lucidum polysaccharides exhaustive group（D），black Ganoderma lucidum polysaccharides exhaustive rest group（E）. According to regulations，five groups of Wistar rats while doing endurance exercise treadmill 30 d，D，E daily prescribed dose gavage black Ganoderma lucidum polysaccharides，after the last exercise training，the A group were sacrificed in a quiet situation，detecting biochemical indicators；make additional 4 groups do Exhausted after strenuous exercise，the B，D sacrificed measure relevant indicators；make C，E rat rest after 12 h，sacrificed and detect targets. The rats taking black Ganoderma lucidum polysaccharides，GSH-Px vitality，SOD activity and -SH content significantly increased，MDA decreased significantly. Description which can enhance the body's antioxidant capacity. Mitochondrial activity was significantly enhanced. After the break 12 h，the liver tissue NOS activity，NO content and mitochondrial index almost reached the original level. Black Ganoderma lucidum polysaccharides can be drawn taking can enhance the body's ability to recover，enhanced resistance to fatigue. Taking black Ganoderma lucidum polysaccharides can enhance the function of rat anti-fatigue and anti-oxidation，improve exercise capacity in rats，fatigue after exercise to strengthen resilience.

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MO Shuangyuan, LIANG Jian. Study of Ganoderma lucidum Polysaccharides on Rat Anti-Fatigue and Anti-Oxidant Effect[J]. Journal of Food Science and Biotechnology,2018,37(5):555-559.

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