Study on the Anti-Fatigue Activity of the Compound of Rhodiola

doi:10.3969/j.issn.1673-1689.2019.08.019

Home > Archive>Volume 38, Issue 8, 2019 >134-141. DOI:10.3969/j.issn.1673-1689.2019.08.019

Study on the Anti-Fatigue Activity of the Compound of Rhodiola
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                        10.3969/j.issn.1673-1689.2019.08.019
                    
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According to the theories of traditional Chinese medicine，we selected the Angelica，Schisandra，Cistanche，Chinese wolfberry，Polygonatum from the commonly used traditional Chinese medicine to relieve the fatigue in combined with Rhodiola，in order to improve the anti-fatigue activity. Kunming male mice were randomly divided into 6 groups：the quiet control group，the swimming control group，formula group I，formula group II，formula group III，and single Rhodiola group. All mice were subjected to gavage administration for 30 days. Results showed that the drugs could significantly prolong the swimming time of mice，decrease the content of serum BUN，blood LA，increase the content of liver glycogen. Compared with single Rhodiola group，formulation II and III displayed better activities，while there was no significant difference between formula group I and single Rhodiola group. Each group was further investigated with SDH，CK，ATP enzyme activities in swimming mice. By comprehensive comparison，formula group III proved the best anti-fatigue effect，indicating the Chinese traditional medicines in formula III other than Rhodiola had a good synergy effect with it，and that may have some directive significance for the development of novel anti-fatigue health products.

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GAN Changsheng, WANG Shanshan, LI Hong, CAI Kunliang. Study on the Anti-Fatigue Activity of the Compound of Rhodiola[J]. Journal of Food Science and Biotechnology,2019,38(8):134-141.

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Online: March 27,2020
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