Optimization of Cordycepin Production by Solid-State Fermentation of Cordyceps militaris

doi:10.3969/j.issn.1673-1689.2019.10.005

Home > Archive>Volume 38, Issue 10, 2019 >30-36. DOI:10.3969/j.issn.1673-1689.2019.10.005

Optimization of Cordycepin Production by Solid-State Fermentation of Cordyceps militaris
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                        10.3969/j.issn.1673-1689.2019.10.005
                    
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To improve the production of cordycepin，the experiments were conducted to optimize the production of cordycepin by solid-state fermentation of Cordyceps militaris. Through a series of single-factor experiments，rice was the fermentation substrate，glucose and soybean flour were the optimum carbon source and nitrogen source respectively，the optimum medium compositions and culture conditions were：rice 30 g（particle size 0.90~1.25 mm），solid-liquid ratio（m/v）1∶1.5，glucose 3%（based on substrate，the same below），soybean flour 2%，wheat bran 1%，inoculation amount was 6 mL，seed age was 2 d，fermentation time was 12 d. The optimization results are that cordycepin production reached 4.69%，which is about 6.34 times compared with the initial level（0.74%）.

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YANG Fan, LIU Jinbin, GUAN Zhengbing, LIAO Xiangru, CAI Yujie. Optimization of Cordycepin Production by Solid-State Fermentation of Cordyceps militaris[J]. Journal of Food Science and Biotechnology,2019,38(10):30-36.

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