Effect of Dendrobium Nobile Aqueous Extract on Decreasing Blood Lipid in Rats with Hyperlipidemia

doi:10.3969/j.issn.1673-1689.2019.12.014

Home > Archive>Volume 38, Issue 12, 2019 >97-102. DOI:10.3969/j.issn.1673-1689.2019.12.014

Effect of Dendrobium Nobile Aqueous Extract on Decreasing Blood Lipid in Rats with Hyperlipidemia
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                        10.3969/j.issn.1673-1689.2019.12.014
                    
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Abstract:

To investigate the hypolipidemic effect of Dendrobium nobile Aqueous Extract（DNAE）in hyperlipidemic rats and its mechanisms. Thirty-two Wistar rats were randomly divided into normal control group，hyperlipidemia model group，low and high dose groups（0.425，2.55 g/（kg·d））.The normal control group was fed with normal diet and others three groups were fed with high-fat diet. After administrations for 8 weeks，the contents of serum TG，TC，LDL-C，HDL-C，AST and ALT were measured. The contents of liver MDA，SOD，CAT，GSH-Px，LPL，HL，PHPA and TC，TG，total bile acid in feces were detected. Compared with the model group，DNAE could decrease the contents of serum TG，LDL-C，ALT and liver MDA ，increase the contents of serum HDL-C，increase the activity of liver SOD，GSH-Px，CAT，LPL and HL，increase the contents of feces TG and total bile acid. CONCLUSION：DNAE can obviously decrease blood lipid and therefore it can be applied for treatment of hyperlipidemic rats.

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LI Yi, WANG Hongxin, JIA Qihai, HE Guohua, LYU Wenping. Effect of Dendrobium Nobile Aqueous Extract on Decreasing Blood Lipid in Rats with Hyperlipidemia[J]. Journal of Food Science and Biotechnology,2019,38(12):97-102.

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Online: April 07,2020
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