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Study on Bactericidal Activity and Antibacterial Mechanism of Volatile Oil of Atractylodes chinensis Koidz
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    Abstract:

    To evaluate the bactericidal activity in vitro and study the antibacterial mechanism of Atractylodes chinensis volatile oil. The antibacterial activity of Atractylodes chinensis volatile oil against Escherichia coli, Staphylococcus aureus and Candida albicans was evaluated by the suspension quantitative germicidal test. Its antibacterial mechanism was elucidated by measuring the effects on the leakage rate of extracellular alkaline phosphatase(AKP), soluble protein content and growth curve of the three strains. Volatile oil from Atractylodes chinensis could effectively inhibit or sterilize the tested microorganism. The contents of alkaline phosphatase(AKP) and soluble protein were significantly increased when compared with those in the control group, while the growth of indicators was suppressed significantly. The Atractylodes chinensis volatile oil showed prominent bactericidal activity by changing cell membrane permeability and destroying cell integrity.

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WANG Zhe, JIANG Yuanting, JIN Yuhan, ZHAO Chenyu, LIU Yanli, LIANG Hanqiao, MA Guoxu. Study on Bactericidal Activity and Antibacterial Mechanism of Volatile Oil of Atractylodes chinensis Koidz[J]. Journal of Food Science and Biotechnology,2020,39(12):21-27.

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  • Online: April 06,2021
  • Published: December 25,2020
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