Abstract:The objective of this study is to investigate the anti-fatigue activity of flavonoids from herbahouttuynia(FFH).For this,128 male mice were divided into control group,low-dose FFH treated group,medium-dose FFH treated group and high-dose FFH treated group.The control group was given dH2O and the treatment groups were given FFH(40,80、160 mg/kg) for 28 days.Body weight,blood lactic acid(BLA),serum blood urea nitrogen(BUN),tissue glycogen(liver and glycogen) concentrations in mice were determined.The results demonstrated that FFH extended the exhaustive exercise time of mice,effectively delayed the increasing of blood lactic acid,increasing the storage of tissue glycogen.From the above results,it can draw the conclusion that FFH exhibited significant anti-fatigue activity
